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Home > Product > Antibody > Rabbit Anti-Zeta Opioid Receptor antibody
7 60 protein; 7-60 protein; HGNC:15768; Met enkephalin receptor; met-enkephalin receptor; OGFR; OGFR_HUMAN; opioid growth factor receptor; Protein 7-60; Zeta type opioid receptor; zeta-type opioid receptor
Cat:
SL18487R
Species Reactivity：
Mouse,(predicted: Human,Rat,Cow,Horse,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human Zeta Opioid Receptor:321-420/677
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OGFR) Polyclonal Antibody, Unconjugated (SL18487R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Product PDFs
Datasheet:


The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008]

Function:
Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation.

Subcellular Location:
Cytoplasm. Nucleus. The OGF/OGFR complex is probably translocated to the nucleus.

Tissue Specificity:
Highly expressed in the heart and liver, moderately in skeletal muscle and kidney and to a lesser extent in brain and pancreas. Expressed in fetal tissues including liver and kidney.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the opioid growth factor receptor family.

SWISS:
Q9NZT2

Gene ID:
11054

Database links:

Entrez Gene: 11054 Human

Omim: 606459 Human

SwissProt: Q9NZT2 Human

Unigene: 67896 Human



Picture

Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OGFR) Polyclonal Antibody, Unconjugated (SL18487R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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