[email protected]
Home > Product > Antibody > Rabbit Anti-HDGF antibody
HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2.
Cat:
SL10956R
Species Reactivity：
Human,(predicted: Mouse,Rat,Pig,Cow,Guinea Pig,)
Immunogen：
KLH conjugated synthetic peptide derived from human HDGF:81-180/240
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HDGF) Polyclonal Antibody, Unconjugated (SL10956R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
More
prev next
Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

Subunit:
Monomer, and domain-swapped homodimer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

Similarity:
Belongs to the HDGF family.
Contains 1 PWWP domain.

SWISS:
P51858

Gene ID:
3068

Database links:

Entrez Gene: 3068 Human

Entrez Gene: 15191 Mouse

Entrez Gene: 114499 Rat

Omim: 600339 Human

SwissProt: P51858 Human

SwissProt: P51859 Mouse

SwissProt: Q8VHK7 Rat

Unigene: 506748 Human

Unigene: 292208 Mouse

Unigene: 860 Rat




Picture

Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (HDGF) Polyclonal Antibody, Unconjugated (SL10956R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.