The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]
Function:
Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids.
Similarity:
Contains 1 CRAL-TRIO domain.
Contains 1 GOLD domain.
SWISS:
Q9UDX3
Gene ID:
284904
Database links:
Entrez Gene: 284904 Human
Entrez Gene: 103655 Mouse
Entrez Gene: 498399 Rat
Omim: 612825 Human
SwissProt: Q9UDX3 Human
SwissProt: Q8R0F9 Mouse
Unigene: 517541 Human
Unigene: 337476 Mouse
Unigene: 218654 Rat
| Picture |
Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SEC14L4) Polyclonal Antibody, Unconjugated (SL19610R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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