Rabbit Anti-SH3BP5 antibody

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3BP5_HUMAN; OTTHUMP00000208289; OTTHUMP00000208291; OTTHUMP00000208294; SAB; SH3 binding protein; SH3 domain binding protein 5 (BTK associated); SH3 domain binding protein 5; SH3 domain binding protein that preferentially associates with BTK; SH3

Cat:

SL19752R

Species Reactivity：

Human,Mouse,(predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,)

Immunogen：

KLH conjugated synthetic peptide derived from human SH3BP5:1-100/455

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Ovary (Mouse) Lysate at 40 ugTestis (Mouse) Lysate at 40 ugJurkat (Human) Cell Lysate at 30 ugPrimary: Anti-SH3BP5 (SL19752R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 50 kDObserved band size: 50 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

Subcellular Location:
Mitochondrion.

Tissue Specificity:
Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate.

Similarity:
Belongs to the SH3BP5 family.

SWISS:
O60239

Gene ID:
9467

Database links:

Entrez Gene: 9467 Human

Entrez Gene: 520254 Cow

Entrez Gene: 80851 Human

Entrez Gene: 4856 Mouse

Entrez Gene: 79566 Mouse

Entrez Gene: 117186 Rat

Omim: 605612 Human

SwissProt: Q0V8K7 Cow

SwissProt: O60239 Human

SwissProt: Q7L8J4 Human

SwissProt: Q99LH9 Mouse

SwissProt: Q9Z131 Mouse

SwissProt: Q91Y80 Rat

Unigene: 11005 Cow

Unigene: 257761 Human

Unigene: 726063 Human

Unigene: 290534 Mouse

Unigene: 383198 Mouse

Unigene: 163321 Rat

Picture

Sample:
Ovary (Mouse) Lysate at 40 ug
Testis (Mouse) Lysate at 40 ug
Jurkat (Human) Cell Lysate at 30 ug
Primary: Anti-SH3BP5 (SL19752R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kD
Observed band size: 50 kD

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