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Home > Product > Antibody > Rabbit Anti-ZMIZ2 antibody
2410117E06Rik; D11Bwg0280e; DKFZp761I2123; hZIMP7; KIAA1886; PIAS like protein Zimp7; PIAS-like protein Zimp7; R74931; RGD1309256; RP23-198N14.8; ZIMP7; Zinc finger MIZ domain containing protein 2; Zinc finger MIZ domain-containing protein 2;
Cat:
SL4391R
Species Reactivity：
Mouse,(predicted: Human,Rat,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human ZMIZ2:1-100/920
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (SL4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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Product PDFs
Datasheet:


ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]

Function:
Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors.

Subcellular Location:
Nucleus. Detected at replication foci throughout S phase.

Tissue Specificity:
Expressed most abundantly in testis with lower levels in heart, brain, pancreas, prostate and ovary.

Similarity:
Contains 1 SP-RING-type zinc finger.

SWISS:
Q8NF64

Gene ID:
83637

Database links:

Entrez Gene: 83637 Human

Entrez Gene: 52915 Mouse

Entrez Gene: 289783 Rat

Entrez Gene: 6378 Rat

Omim: 611196 Human

SwissProt: Q8NF64 Human

SwissProt: Q8CIE2 Mouse

Unigene: 600681 Human

Unigene: 77978 Human

Unigene: 1144 Mouse



Picture

Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ZMIZ2) Polyclonal Antibody, Unconjugated (SL4391R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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