Rabbit Anti-N-cadherin antibody

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Cadherin 2; Cadherin 2 N cadherin neuronal; Cadherin 2 type 1; Cadherin 2 type 1 N cadherin neuronal; cadherin 2 type 1 N-cadherin neuronal; Cadherin2; Calcium dependent adhesion protein neuronal; CD325; CD325 antigen; CDH2; CDHN; CDw325; CDw325 antigen;

Cat:

SL20622R

Species Reactivity：

Human,Mouse,Rat,(predicted: Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human N-cadherin:701-800/906

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane 1: A549 (Human) Cell Lysate at 30 ugLane 2: SH-SY5Y (Human) Cell Lysate at 30 ugLane 3: U251 (Human) Cell Lysate at 30 ugLane 4: MCF-7 (Human) Cell Lysate at 30 ugPrimary: Anti-N-cadherin (SL20622R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 130 kDObserved band size: 130 kDSample: Lane 1: Testis (Mouse) Lysate at 40 ugLane 2: Cerebrum (Mouse) Lysate at 40 ugLane 3: Testis (Rat) Lysate at 40 ugLane 4: Cerebellum (Rat) Lysate at 40 ugLane 5: Panc-1 (Human) Cell Lysate at 30 ugLane 6: A549 (Human) Cell Lysate at 30 ugLane 7: SH-SY5Y (Human) Cell Lysate at 30 ugLane 8: U251 (Human) Cell Lysate at 30 ugPrimary: Anti-N-cadherin (SL20622R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 130 kDObserved band size: 130 kDSample: Cerebrum (Mouse) Lysate at 40 ugPrimary: Anti-N-cadherin (SL20622R) at 1/300 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 100 kDObserved band size: 105/125 kD

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density.

Similarity:
Contains 5 cadherin domains.

SWISS:
P19022

Gene ID:
1000

Database links:

Entrez Gene: 1000 Human

Entrez Gene: 281062 Cow

Entrez Gene: 12558 Mouse

Entrez Gene: 83501 Rat

Omim: 114020 Human

SwissProt: P19022 Human

SwissProt: P15116 Mouse

SwissProt: Q9Z1Y3 Rat

Unigene: 464829 Human

Unigene: 606106 Human

Unigene: 257437 Mouse

Unigene: 2640 Rat

细胞粘附蛋白（Call Adhesion Protein）
N-钙粘附分子属于依赖钙离子的细胞间糖蛋白粘附分子的一部分,主要是参与细胞间同源性粘附,调控和介导细胞间相互反应。 Picture

Sample:
Lane 1: Testis (Mouse) Lysate at 40 ug
Lane 2: Cerebrum (Mouse) Lysate at 40 ug
Lane 3: Testis (Rat) Lysate at 40 ug
Lane 4: Cerebellum (Rat) Lysate at 40 ug
Lane 5: Panc-1 (Human) Cell Lysate at 30 ug
Lane 6: A549 (Human) Cell Lysate at 30 ug
Lane 7: SH-SY5Y (Human) Cell Lysate at 30 ug
Lane 8: U251 (Human) Cell Lysate at 30 ug
Primary: Anti-N-cadherin (SL20622R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 130 kD
Observed band size: 130 kD

Sample:
Cerebrum (Mouse) Lysate at 40 ug
Primary: Anti-N-cadherin (SL20622R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 100 kD
Observed band size: 105/125 kD

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