GAS2L3 (Growth arrest-specific 2 like 3) a member of the GAS2 family, is similar in sequence to the mouse protein GAS2, an actin-associated protein expressed at high levels in growth-arrested cells. The specific function of this protein is unknown.
Function:
Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network.
Subunit:
Interacts (via CH domain) with F-actin. Interacts (via C terminus) with microtubules.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Expressed in the pancreas, heart, liver, placenta, brain, skeletal muscle, kidney and lung.
Similarity:
Belongs to the GAS2 family.
Contains 1 CH (calponin-homology) domain.
Contains 1 GAR domain.
SWISS:
Q86XJ1
Gene ID:
283431
Database links:
Entrez Gene: 283431 Human
SwissProt: Q86XJ1 Human
Unigene: 20575 Human
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Paraformaldehyde-fixed, paraffin embedded (Rat skeletal muscle); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (GAS2L3) Polyclonal Antibody, Unconjugated (SL23297R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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