Home > Product > Antibody > Rabbit Anti-EGFL6 antibody
EGF like domain multiple 6; EGF repeat containing protein 6; EGF-like protein 6; EGF-like-domain multiple 6; egfl6; EGFL6_HUMAN; epidermal growth factor like protein 6; Epidermal growth factor-like protein 6; MAEG; MAM and EGF domain containing; MAM and E
Cat:
SL21427R
Species Reactivity:
Human,(predicted: Mouse,Rat,Dog,Cow,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human EGFL6:481-581/553
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Sample: A549(Human) Cell Lysate at 30 ugSH-SY5Y (Human) Cell Lysate at 30 ugPrimary: Anti- EGFL6 (SL21427R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 59 kDObserved band size: 59 kD
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Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a member of the epidermal growth factor(EGF) repeat superfamily. Members of this superfamily arecharacterized by the presence of EGF-like repeats and are ofteninvolved in the regulation of cell cycle, proliferation, anddevelopmental processes. The gene product contains a signalpeptide, suggesting that it is secreted; an EGF repeat regionconsisting of 4 complete EGF-like repeats and 1 partial EGF-likerepeat, 3 of which have a calcium-binding consensus sequence; anarg-gly-asp integrin association motif; and a MAM domain, which isbelieved to have an adhesive function. This gene is expressed earlyduring development, and its expression has been detected in lungand meningioma tumors. [provided by RefSeq, Jul 2008].

Function:
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.

Subcellular Location:
Secreted, extracellular space, extracellularmatrix, basement membrane (By similarity).

Similarity:
Belongs to the nephronectin family.
Contains 5 EGF-like domains.
Contains 1 MAM domain.

SWISS:
Q8IUX8

Gene ID:
25975

Database links:

Entrez Gene: 25975 Human

Entrez Gene: 54156 Mouse

Entrez Gene: 317470 Rat

Omim: 300239 Human

SwissProt: Q8IUX8 Human

SwissProt: Q9JJZ5 Mouse



Picture

Sample:
A549(Human) Cell Lysate at 30 ug
SH-SY5Y (Human) Cell Lysate at 30 ug
Primary: Anti- EGFL6 (SL21427R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 59 kD
Observed band size: 59 kD
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