Home > Product > Antibody > Rabbit Anti-Neurotrophin 3 antibody
HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; Neurotrophin 3 precursor; Neurotrophin-3; Neurotrophin3; NGF 2; NGF-2; NGF2; NT 3; NT-3; NT3; NTF 3; NTF3; NTF3_HUMAN.
Cat:
SL21489R
Species Reactivity:
Rat,(predicted: Human,Mouse,)
Immunogen:
KLH conjugated synthetic peptide derived from human Neurotrophin 3 :131-230/257
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Product Overview:
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Neurotrophin 3) Polyclonal Antibody, Unconjugated (SL21489R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
More
Unit:
Price: $
Product PDFs
Datasheet:


The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008].

Function:
Seems to promote the survival of visceral and proprioceptive sensory neurons.

Subcellular Location:
Secreted.

Tissue Specificity:
Brain and peripheral tissues.

Similarity:
Belongs to the NGF-beta family.

SWISS:
P20783

Gene ID:
4908

Database links:
Entrez Gene: 4908 Human

Entrez Gene: 18205 Mouse

Entrez Gene: 81737 Rat

Omim: 162660 Human

SwissProt: P20783 Human

SwissProt: P20181 Mouse

SwissProt: P18280 Rat

Unigene: 99171 Human

Unigene: 267570 Mouse

Unigene: 9715 Rat



神经生物学相关蛋白(Neurobiology) 一种内源型神经递质,分子量为28kDa的碱性多肽,属神经营养蛋白家族。与NGF和BDNF具有序列同源性,为培养的神经嵴细胞的促细胞分裂剂。此抗体与NGF、BDNF无交叉反应。 Picture

Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Neurotrophin 3) Polyclonal Antibody, Unconjugated (SL21489R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.