Home > Product > Antibody > Rabbit Anti-Chromogranin B antibody
Secretogranin I; CCB peptide; Cg B; CgB; CHGB; ChromograninB; GAWK peptide; SCG1; Secretogranin 1; Secretogranin B; Secretogranin I; Secretogranin I precursor; SgI; SCG1_HUMAN; Secretogranin-1; Chromogranin-B.
Cat:
SL0543R
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from mouse CGB:601-677/677
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009].

Function:
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Subcellular Location:
Secreted. Note=Neuroendocrine and endocrine secretory granules.

Tissue Specificity:
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.

Post-translational modifications:
Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.
O-glycosylated.

Similarity:
Belongs to the chromogranin/secretogranin protein family.

SWISS:
P16014

Gene ID:
12653

Database links:

Entrez Gene: 1114 Human

Entrez Gene: 12653 Mouse

Entrez Gene: 24259 Rat

Omim: 118920 Human

SwissProt: P05060 Human

SwissProt: P16014 Mouse

SwissProt: O35314 Rat

Unigene: 516874 Human

Unigene: 11090 Rat



嗜铬粒素B在肾上腺 垂体 胸腺 子宫 卵巢等神经内分泌组织表达该蛋白成分较多。
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