Rabbit Anti-WNT10A antibody

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wingless-type MMTV integration site family, member 10A; WNT 10A; WNT10 A; WNT10A; Protein Wnt-10a; WN10A_HUMAN.

Cat:

SL1947R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human WNT10A:301-417/417

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Similarity:
Belongs to the Wnt family.

SWISS:
Q9GZT5

Gene ID:
80326

Database links:

Entrez Gene: 80326 Human

Entrez Gene: 2489 Mouse

Omim: 606268 Human

SwissProt: Q9GZT5 Human

SwissProt: P70701 Mouse

Unigene: 121540 Human

Unigene: 5130 Mouse

Wnt通路与人类多种肿瘤的发生有关,WNT10A主要用于消化系统肿瘤的研究。

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