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Rabbit Anti-CXCL15 antibody
CXCL15 (Lungkine) is a CXC chemokine that is expressed in murine lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is elevated in response to inflammation, at which time it acts to specifically recruit neutrophils and direct them into the lung airway.
Function:
Chemotactic for neutrophils. May be involved in lung-specific neutrophil trafficking during normal and inflammatory conditions.
Subcellular Location:
Secreted.
Tissue Specificity:
Expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. Expressed at low levels in fetal lung.
Similarity:
Belongs to the intercrine alpha (chemokine CxC) family.
SWISS:
Q9WVL7
Gene ID:
20309
Database links:
Entrez Gene: 20309 Mouse
SwissProt: Q9WVL7 Mouse
Unigene: 64326 Mouse
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