Rabbit Anti-CDC34B antibody

Home > Product > Antibody > Rabbit Anti-CDC34B antibody

CDC34B; E2 CDC34B; UBE2R2; Ubiquitin carrier protein R2; Ubiquitin conjugating enzyme E2 CDC34B; Ubiquitin conjugating enzyme E2 R2; Ubiquitin conjugating enzyme E2R 2; Ubiquitin conjugating enzyme UBC3B; Ubiquitin protein ligase R2.

Cat:

SL3813R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human CDC34B:101-200/238

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

UBC3B is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes monoubiquitination and 'Lys-48'-linked polyubiquitination. May be involved in degradation of katenin.

Subunit:
When phosphorylated, interacts with beta-TrCP (BTRC).

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.

SWISS:
Q712K3

Gene ID:
54926

Database links:

Entrez Gene: 54926 Human

Entrez Gene: 67615 Mouse

Entrez Gene: 299677 Rat

Omim: 612506 Human

SwissProt: Q712K3 Human

SwissProt: Q6ZWZ2 Mouse

Unigene: 643648 Human

Unigene: 725177 Human

Unigene: 389540 Mouse

Product Feedback Wall