Rabbit Anti-Growth Arrest Specific Protein 7 antibody

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GAS 7; GAS-7; Gas7; GAS7_HUMAN; Growth arrest specific 7; Growth arrest-specific protein 7; KIAA0394; MGC1348; MLL/GAS7; MLL/GAS7 fusion protein.

Cat:

SL4279R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human GAS7/Growth Arrest Specific Protein 7:361-476/476

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Growth arrest specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. It may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Several transcript variants encoding proteins which vary in the N terminus have been described.

Function:
May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

Subcellular Location:
Cytoplasm (By similarity).

DISEASE:
Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.

Similarity:
Contains 1 FCH domain.
Contains 1 SH3 domain.
Contains 1 WW domain.

SWISS:
O60861

Gene ID:
8522

Database links:

Entrez Gene: 8522 Human

Omim: 603127 Human

SwissProt: O60861 Human

SwissProt: O55148 Rat

Unigene: 258855 Human

Unigene: 462214 Human

Unigene: 17160 Rat

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