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Home > Product > Antibody > Rabbit Anti-PTPIP51 antibody
Cerebral protein 10; Family with sequence similarity 82 member C; hRMD 3; Microtubule associated protein; Protein FAM82A2; Protein FAM82C; Protein tyrosine phosphatase interacting protein 51; PTPIP51; Regulator of microtubule dynamics 3; Regulator of micr
Cat:
SL5719R
Species Reactivity：
Human,Mouse,Rat,(predicted: Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human PTPIP51/FAM82A2:101-180/470
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
WB=1:500-2000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Product Overview：
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Human U251 cell lysates Primary: Anti- PTPIP51 (SL5719R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 52 kDObserved band size: 52 kD
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Price: $
Product PDFs
Datasheet:


RMDN3 (Regulator Of Microtubule Dynamics 3) is a Protein Coding gene. Diseases associated with RMDN3 include Amyotrophic Lateral Sclerosis 16, Juvenile and Amyotrophic Lateral Sclerosis 8. An important paralog of this gene is RMDN2.

Function:
Involved in cellular calcium homeostasis regulation. May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis.

Subunit:
Interacts with PTPN2. Interacts with microtubules. Interacts with VAPB.

Subcellular Location:
Mitochondrion membrane; Single-pass membrane protein. Mitochondrion outer membrane. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase localizes in the cytoplasm, and during mitosis localizes to the spindle microtubules and spindle poles.

Tissue Specificity:
Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed.

Similarity:
Belongs to the RMDN family.

SWISS:
Q96TC7

Gene ID:
55177

Database links:




Picture

Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Lane 3: Human U251 cell lysates
Primary: Anti- PTPIP51 (SL5719R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
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