FGF17 belongs to the heparin-binding growth factors family. It may be a signaling molecule in the induction and patterning of the embryonic brain and is preferentially expressed in the embryonic brain. There are two named isoforms.
Function:
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.
Subunit:
Interacts with FGFR3 and FGFR4.
Subcellular Location:
Secreted.
Tissue Specificity:
Preferentially expressed in the embryonic brain.
Similarity:
Belongs to the heparin-binding growth factors family.
SWISS:
O60258
Gene ID:
8822
Database links:
Entrez Gene: 8822 Human
Omim: 603725 Human
SwissProt: O60258 Human
Unigene: 248192 Human
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