Rabbit Anti-CDK5RAP3 antibody

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C53; CDK5 activator binding protein C53; CDK5 regulatory subunit associated protein 3; HSF 27; HSF27; IC53; Ischemic heart CDK5 activator binding protein C53; LXXLL/leucine zipper containing ARFbinding protein; LZAP; MST016; OK/SW cl.114; PP1553; CK5P3_HU

Cat:

SL6518R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human CDK5RAP3:51-150/506

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.

Function:
CDK5RAP3 may be involved in cell proliferation through regulation of the CDK5 family by interaction with CDK5 receptor 1.

Subunit:
Interacts with CDK5R1. This interaction is prevented by the association between CDK5R1 and CDK5RAP3. Interacts with the enteric adenovirus serotype 41 fiber protein. Interacts with UFL1.

Tissue Specificity:
Ubiquitous. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform 3 is expressed in kidney, liver, skeletal muscle and placenta.

Post-translational modifications:
Phosphorylated in vitro by CDK5

Similarity:
Belongs to the CDK5RAP3 family.

SWISS:
Q96JB5

Gene ID:
80279

Database links:

Entrez Gene: 80279 Human

Entrez Gene: 80280 Mouse

Entrez Gene: 80278 Rat

Omim: 608202 Human

SwissProt: Q96JB5 Human

SwissProt: Q99LM2 Mouse

SwissProt: Q9JLH7 Rat

Unigene: 20157 Human

Unigene: 28297 Mouse

Unigene: 3727 Rat

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