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Home > Product > Antibody > Rabbit Anti-DUSP22 antibody
Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; MKPX; DUS22_HUMAN.
Cat:
SL7066R
Species Reactivity：
(predicted: Human,Mouse,Rat,Cow,Rabbit,)
Immunogen：
KLH conjugated synthetic peptide derived from human DUSP22/JSP1:13-100/184
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
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Product PDFs
Datasheet:


Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK)

Function:
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).

Subunit:
Monomer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

Post-translational modifications:
Myristoylation regulates subcellular location, and is necessary for activation of JNK.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Contains 1 tyrosine-protein phosphatase domain.

SWISS:
Q9NRW4

Gene ID:
56940

Database links:

Entrez Gene: 56940 Human

Entrez Gene: 105352 Mouse

Entrez Gene: 361242 Rat

SwissProt: Q9NRW4 Human

SwissProt: Q99N11 Mouse

Unigene: 29106 Human

Unigene: 289646 Mouse



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