Rabbit Anti-GTSE1 antibody | Sunlong Medical

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G2 and S phase-expressed protein 1; B99; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; GTSE 1; GTSE-1; GTSE1_HUMAN.

Cat:

SL7611R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human GTSE1/G2 and S phase expressed 1:51-150/720

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.

Function:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.

Subcellular Location:
Cytoplasm, cytoskeleton. Note=Associated with microtubules.

Post-translational modifications:
Phosphorylated in mitosis (By similarity).

SWISS:
Q9NYZ3

Gene ID:
51512

Database links:

Entrez Gene: 51512 Human

Entrez Gene: 29870 Mouse

Entrez Gene: 300126 Rat

Omim: 607477 Human

SwissProt: Q9NYZ3 Human

SwissProt: Q8R080 Mouse

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