This gene encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
Function:
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity).
Subcellular Location:
Mitochondrion (By similarity). Note=May be associated with the inner and the outer mitochondrial membrane (By similarity).
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the MTFR1/FAM54 family.
SWISS:
Q15390
Gene ID:
9650
Database links:
UniProtKB/Swiss-Prot: Q15390.2
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