Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of this small, 76 amino acid protein is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. Many ubiquitin-like proteins function as post-translational protein modifiers, such as members of the SUMO protein family, however some ubiquitin-like proteins regulate protein-protein interactions and cell cycle events, thereby functioning outside of the traditional ubiquitination pathway. UBTD1 (Ubiquitin domain-containing protein 1) is a 227 amino acid protein containing one SLCterminal Ubiquitin-like (UBQ) domain. With only one UBQ domain, it is likely that UBTD1 is capable of conjugation to other proteins and mostly functions in similar ways to ubiquitin in the modification of post-translational proteins.
Similarity:
Contains 1 ubiquitin-like domain.
SWISS:
Q9HAC8
Gene ID:
80019
Database links:
Entrez Gene: 80019 Human
Entrez Gene: 226122 Mouse
Entrez Gene: 309373 Rat
GenBank: NP_079230 Human
SwissProt: Q9HAC8 Human
SwissProt: Q91WB7 Mouse
SwissProt: Q68FV8 Rat
Unigene: 500724 Human
Unigene: 22948 Mouse
Unigene: 138196 Rat
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