Home > Product > Antibody > Rabbit Anti-NSP5/NSP 5 alpha 3 alpha antibody
Cytokinesis and spindle organization B; NSP 5 alpha 3 alpha; Cytospin B; FLJ36955; HCMOGT 1; NSP; NSP5; Nuclear structure protein 5; SPECC1; Spectrin domain with coiled coils 1; Sperm antigen HCMOGT 1; Sperm antigen with calponin homology and coiled coil
Cat:
SL7816R
Species Reactivity:
Rat,(predicted: Human,Dog,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human NSP5:601-700/1068
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


NSP type 5 alpha 3 alpha is a novel structure protein belonging to the cytospin-A family, that may play a role in nuclear function during cell division. It is also highly expressed in certain tumor cell lines, suggesting that it may serve as a good tumor marker. It was was cloned as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in testis. Barely detectablein other tissues. Also highly expressed in some cancer cell lines.

DISEASE:
Note=A chromosomal aberration involving CYTSB may be acause of juvenile myelomonocytic leukemia. Translocationt(5;17)(q33;p11.2) with PDGFRB.

Similarity:
Belongs to the cytospin-A family.
Contains 1 CH (calponin-homology) domain.

SWISS:
Q5M775

Gene ID:
92521

Database links:

Entrez Gene: 92521 Human

Omim: 608793 Human

SwissProt: Q5M775 Human

Unigene: 431045 Human



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