Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer a labile 4Fe-4S cluster to target apoproteins.
Function:
Component of the cytosolic iron-sulfur (Fe/S) proteinassembly machinery. Required for maturation of extramitochondrialFe/S proteins. May bind and transfer a labile 4Fe-4S cluster totarget apoproteins (By similarity).
Subunit:
Interacts with KIFC1 (By similarity). Interacts withNUBP1.
Subcellular Location:
Nucleus (By similarity). Cytoplasm,cytoskeleton, centrosome (By similarity). Note=Enriched at thecentrosomes during mitosis (By similarity).
Tissue Specificity:
Widely expressed with highest expression inskeletal muscle.
Similarity:
Belongs to the Mrp/NBP35 ATP-binding proteins family.NUBP2/CFD1 subfamily.
SWISS:
Q9Y5Y2
Gene ID:
10101
Database links:
Entrez Gene: 10101 Human
Omim: 610779 Human
SwissProt: Q9Y5Y2 Human
Unigene: 256549 Human
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