Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
Function:
Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
Subunit:
Homooligomerize (By similarity). Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HISLV1. Interacts with SARS-CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the SGT family. Contains 3 TPR repeats.
SWISS:
O43765
Gene ID:
6449
Database links:
UniProtKB/Swiss-Prot: O43765.1
Entrez Gene: 6449 Human
Entrez Gene: 52551 Mouse
Omim: 603419 Human
SwissProt: O43765 Human
SwissProt: Q6FIA9 Human
SwissProt: Q3TN35 Mouse
SwissProt: Q8BJU0 Mouse
Unigene: 203910 Human
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