Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Subunit:
Interacts with and phosphorylates TORC2/CRTC2.
Subcellular Location:
Cytoplasm
Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Contains 1 protein kinase domain.
Contains 1 UBA domain.
SWISS:
Q9H0K1
Gene ID:
23235
Database links:
Entrez Gene: 23235 Human
Entrez Gene: 235344 Mouse
Entrez Gene: 315649 Rat
Omim: 608973 Human
SwissProt: Q9H0K1 Human
SwissProt: Q8CFH6 Mouse
Unigene: 269128 Human
Unigene: 104932 Mouse
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