FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Tissue Specificity:
Expressed in esophageal squamous cell carcinomas.
Similarity:
Belongs to the FAM84 family.
SWISS:
Q96KN1
Gene ID:
157638
Database links:
Entrez Gene: 157638 Human
Omim: 609483 Human
SwissProt: Q96KN1 Human
Unigene: 124951 Human
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