Rabbit Anti-SNAPC3 antibody

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SNAP50; SNAPc50; Proximal sequence element-binding transcription factor subunit beta; PSE binding factor subunit beta; PTF subunit beta; PTFbeta; small nuclear RNA activating complex, polypeptide 3, 50kDa; Small nuclear RNA-activating complex polypeptide

Cat:

SL8452R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human SNAPC3:331-411/411

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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SNAPC3 is part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. SNAPC3 binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. SNAPC3 recruits TBP and BRF2 to the U6 snRNA TATA box.

Function:
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

Subunit:
Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.

Subcellular Location:
Nuclear

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

SWISS:
Q92966

Gene ID:
6619

Database links:

Entrez Gene: 6619 Human

Entrez Gene: 77634 Mouse

Entrez Gene: 362537 Rat

Omim: 602348 Human

SwissProt: Q92966 Human

SwissProt: Q9D2C9 Mouse

SwissProt: Q5BK68 Rat

Unigene: 546299 Human

Unigene: 271985 Mouse

Unigene: 482328 Mouse

Unigene: 204909 Rat

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