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Rabbit Anti-RNF167 antibody
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Function:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Subunit:
Interacts with SLC22A18.
Subcellular Location:
Endomembrane system. Targeted to cytoplasmic membranes.
Tissue Specificity:
Strongly expressed in the kidney and liver (at protein level).
Post-translational modifications:
Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1.
Similarity:
Contains 1 PA (protease associated) domain.
Contains 1 RING-type zinc finger.
SWISS:
Q9H6Y7
Gene ID:
26001
Database links:
Entrez Gene: 26001 Human
SwissProt: Q9H6Y7 Human
Unigene: 7158 Human
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