Rabbit Anti-C1orf2 antibody

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Chromosome 1 open reading frame 2; COTE1; F189B_HUMAN; FAM189B; Family with sequence similarity 189 member B; Hypothetical protein LOC10712; Protein COTE1; Protein FAM189B.

Cat:

SL9782R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Horse,Guinea Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human C1orf2:151-250/668

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500IF=1:50-200（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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COTE1, also known as FAM189B (family with sequence similarity 189, member B), is a 668 amino acid multi-pass membrane protein that is widely expressed and belongs to the FAM189 family. Existing as two alternatively spliced isoforms, COTE1 is encoded by a gene that maps to human chromosome 1q22. As the largest human chromosome, chromosome 1 spans about 260 million base pairs and makes up approximately 8% of the human genome. Hutchinson-Gilford progeria, a rare aging disorder, is associated with the LMNA gene which is located on chromosome 1. Familial adenomatous polyposis, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Subcellular Location:
Membrane.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the FAM189 family.

SWISS:
P81408

Gene ID:
10712

Database links:

Entrez Gene: 10712 Human

Entrez Gene: 68521 Mouse

Entrez Gene: 310128 Rat

SwissProt: P81408 Human

SwissProt: Q5HZJ5 Mouse

Unigene: 348308 Human

Unigene: 274708 Mouse

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