Rabbit Anti-C14orf130 antibody

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Chromosome 14 open reading frame 130; N recognin 7; Putative E3 ubiquitin-protein ligase UBR7; Ubiquitin protein ligase E3 component n-recognin 7 (putative); UBR7; UBR 7; UBR-7; UBR7_HUMAN.

Cat:

SL9616R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human UBR7/C14orf130:331-425/425

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Ubr7 is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.

Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity).

Similarity:
Contains 1 PHD-type zinc finger.
Contains 1 UBR-type zinc finger.

SWISS:
Q8N806

Gene ID:
55148

Database links:

Entrez Gene: 55148 Human

Entrez Gene: 66622 Mouse

Entrez Gene: 314399 Rat

Omim: 613816 Human

SwissProt: Q8N806 Human

SwissProt: Q8BU04 Mouse

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