The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome. The FAM70A gene product has been provisionally designated FAM70A pending further characterization.
Subcellular Location:
Membrane; Multi-pass membrane protein
Similarity:
Belongs to the TMEM255 family.
SWISS:
Q5JRV8
Gene ID:
55026
Database links:
Entrez Gene: 55026 Human
Entrez Gene: 245386 Mouse
Entrez Gene: 313453 Rat
SwissProt: Q9BE63 Cynomolgus monkey
SwissProt: Q5JRV8 Human
SwissProt: Q8SHW5 Mouse
SwissProt: Q7TMP6 Rat
Unigene: 437563 Human
Unigene: 72979 Mouse
Unigene: 163441 Rat
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