Rabbit Anti-ADGRE1 antibody

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F4/80; Adhesion G protein-coupled receptor E1; Cell surface glycoprotein EMR1; Cell surface glycoprotein F4/80; DD7A5 7; Egf like module containing mucin like hormone receptor like 1; Egf like module containing mucin like hormone receptor like sequence 1;

Cat:

SL11182R

Species Reactivity：

Human,Mouse,(predicted: Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human ADGRE1:401-500/886<Extracellular>

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 ugLane 2: HL60 (Human) Cell Lysate at 30 ugPrimary: Anti-EMR1/ F4/80 (SL11182R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 100-110 kDObserved band size: 125 kD

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Unit:

Price: $220.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its SLCterminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Function:
Could be involved in cell-cell interactions.

Subunit:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. Contains 6 EGF-like domains. Contains 1 GPS domain.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Wide expression; increased levels in peripheral blood mononuclear cells.

Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 6 EGF-like domains.
Contains 1 GPS domain.

SWISS:
Q14246

Gene ID:
2015

Database links:

Entrez Gene: 2015 Human

Entrez Gene: 13733 Mouse

Omim: 600493 Human

SwissProt: Q14246 Human

SwissProt: Q61549 Mouse

Unigene: 2375 Human

Unigene: 2254 Mouse

Picture

Sample:
Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 ug
Lane 2: HL60 (Human) Cell Lysate at 30 ug
Primary: Anti-EMR1/ F4/80 (SL11182R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 100-110 kD
Observed band size: 125 kD

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Specific References (12) | SL11182R has been referenced in 12 publications.

[IF=2.939] Yang R et al. Cordycepin Attenuates IFN-γ-Induced Macrophage IP-10 and Mig Expressions by Inhibiting STAT1 Activity in CFA-Induced Inflammation Mice Model. Inflammation. 2019 Dec 23. IHSLCP ; Mouse.

PubMed:31873836

[IF=3.041] An G et al. Effects of CCL5 on the biological behavior of breast cancer and the mechanisms of its interaction with tumor‑associated macrophages. Oncol Rep. 2019 Dec;42(6):2499-2511. IHSLCP ; Human.

PubMed:31578575

[IF=3.06] Li T et al. Withanolides, extracted from Datura metel L. inhibit keratinocyte proliferation and imiquimod- induced psoriasis-like dermatitis via the STAT3/P38/ERK1/2 pathway. Molecules. 2019 Jul 17;24(14). pii: E2596. WB ; Mouse.

PubMed:31319488

[IF=2.939] Wei S et al.Overexpression of Toll-like receptor 4 enhances LPS-induced inflammatory response and inhibits Salmonella Typhimurium growth in ovine macrophages.(2018) Eur J Cell Biol. ICF ; sheep.

PubMed:30522781

[IF=2.148] Zhang M et al. The role of TrkA in the promoting wounding-healing effect of CD271 on epidermal stem cells. (2018) Arch. Dermatol. Res. IHC ; mouse.

PubMed:30209580

[IF=2.02] Jiejuan Lai. et al. Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow. Stem Cell Res. 2021 Aug;55:102477 IF,ICC ; Mouse.

PubMed:34343826

[IF=3.943] Quanyu Chen. et al. Hepatocyte growth factor mediates a novel form of hepatic stem/progenitor cell-induced tolerance in a rat xenogeneic liver rejection model. Int Immunopharmacol. 2021 Jan;90:10736 IHC ; Hamster, Rat.

PubMed:33221167

[IF=4.225] Liu Yi. et al. Overexpression of Activating Transcription Factor 3 Alleviates Cardiac Microvascular Ischemia/Reperfusion Injury in Rats. Front Pharmacol. 2021 Feb;12:71 IF,IHC ; Rat.

PubMed:10.3389/fphar.2021.598959

[IF=5.162] Sun Y et al. Apple polysaccharide prevents from colitis-associated carcinogenesis through regulating macrophage polarization. Int J Biol Macromol . 2020 Oct 15;161:704-711. WB&IHF-P ; Mouse.

PubMed:32544579

[IF=13.903] Tang Y et al. Overcoming the Reticuloendothelial System Barrier to Drug Delivery with a "Don't-Eat-Us" Strategy. ACS Nano. 2019 Nov 5. IHF ; Mouse.

PubMed:31689086

[IF=3.388] Liu X et al. KDM3A inhibition modulates macrophage polarization to aggravate post-MI injuries and accelerates adverse ventricular remodeling via an IRF4 signaling pathway. Cell Signal. 2019 Sep 9;64:109415. ICF ; Mouse.

PubMed:31513837

[IF=3.04] Jiang X et al.Loss of MD1 exacerbates myocardial ischemia/reperfusion injury and susceptibility to ventricular arrhythmia.(2018)Eur J Pharmacol;844:79-86. IHC ; Mouse.

PubMed:30458167