Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Function:
Odorant receptor.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Exclusively expressed in the prostate. Up-regulated in prostate cancers.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q9H255
Gene ID:
81285
Database links:
Entrez Gene: 81285 Human
Entrez Gene: 510115 Cow
Entrez Gene: 100328820 Rabbit
Entrez Gene: 170816 Rat
Omim: 611268 Human
SwissProt: Q9H255 Human
SwissProt: O88628 Rat
Unigene: 501758 Human
Unigene: 606330 Human
Unigene: 12541 Rat
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