Home > Product > Antibody > Rabbit Anti-DNER antibody
Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.
Cat:
SL12115R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Cow,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human DNER:185-300/737<Extracellular>
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Subunit:
Interacts with AP1G1. Interacts with NOTCH1.

Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.

Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.

Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.

SWISS:
Q8NFT8

Gene ID:
92737

Database links:

Entrez Gene: 92737 Human

Entrez Gene: 227325 Mouse

Entrez Gene: 316573 Rat

Omim: 607299 Human

SwissProt: Q8NFT8 Human

SwissProt: Q8JZM4 Mouse

Unigene: 234074 Human

Unigene: 292560 Mouse



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