DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types.
Subcellular Location:
Nuclear
Similarity:
Belongs to the H2.0 homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
Q6ZNG2
Gene ID:
88097
Database links:
Entrez Gene: 88097 Human
Entrez Gene: 223843 Mouse
Entrez Gene: 541457 Rat
SwissProt: Q6ZNG2 Human
Unigene: 302764 Human
Unigene: 152937 Mouse
Unigene: 93216 Rat
Picture |
Sample:
Cerebrum(Mouse) Lysate at 40 ug
Cerebrum(Rat) Lysate at 40 ug
293T(Human) Cell Lysate at 30 ug
Primary: Anti-DBX2 (SL12149R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 40 kD
|
|
|