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Rabbit Anti-Calcyphosine 2 antibody
CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Subcellular Location:
Cell membrane
Tissue Specificity:
Abundantly expressed in many tissues. Expressed in brain, colon, heart, kidney, liver, lung, liver, pancreas, placenta, skeletal muscle, testis and thymus. Highest expression in colon, testis, lung, placenta and brain.
Similarity:
Contains 3 EF-hand domains.
SWISS:
Q13938
Gene ID:
828
Database links:
Entrez Gene: 828 Human
Omim: 114212 Human
SwissProt: Q13938 Human
Unigene: 584744 Human
Unigene: 627868 Human
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