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Rabbit Anti-ZNF274 antibody
This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]
74kDa(hu); 94kDa(mo,rat);
Function:
ZNF274 is a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The protein has been suggested to be a transcriptional repressor.
Subunit:
Interacts with SETDB1 and TRIM28/KAP1.
Subcellular Location:
Cytoplasm, Nucleus, nucleolus.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
Contains 2 KRAB domains.
Contains 1 SCAN box domain.
SWISS:
Q96GC6
Gene ID:
10782
Database links:
Entrez Gene: 10782 Human
Omim: 605467 Human
SwissProt: Q96GC6 Human
Unigene: 83761 Human
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