This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]
Subcellular Location:
Nucleus.
Similarity:
Belongs to the TALE/PBX homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
Q9BYU1
Gene ID:
80714
Database links:
Entrez Gene: 80714 Human
Omim: 608127 Human
SwissProt: Q9BYU1 Human
Unigene: 466257 Human
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