Rabbit Anti-LRRFIP2 antibody

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5133400F20Rik; AI850587; DKFZp434H2035; FLJ20248; FLJ22683; FLJ58304; HUFI 2; Leucine rich repeat (in FLII) interacting protein 2; Leucine rich repeat flightless interacting protein 2; Leucine-rich repeat flightless-interacting protein 2; LRR FLII interac

Cat:

SL12438R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human LRRFIP2:1-100/721

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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LRRFIP2 is a 721 amino acid protein that belongs to the LRRFIP family. Ubiquitously expressed, LRRFIP2 acts as an activator of the Wnt signaling pathway and as a positive regulator of NFⅹB activity. LRRFIP2 may be involved in regulating cytokine production in macrophages, suggesting a functional role in the TLR4-mediated inflammatory response. Three isoforms of LRRFIP2 exists due to alternative splicing events.

Function:
May function as activator of the canonical Wnt signaling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin.

Tissue Specificity:
Ubiquitous with higher expression in heart and skeletal muscle.

Similarity:
Belongs to the LRRFIP family.

SWISS:
Q9Y608

Gene ID:
9209

Database links:

Entrez Gene: 9209 Human

Entrez Gene: 71268 Mouse

Entrez Gene: 301035 Rat

Omim: 614043 Human

SwissProt: Q9Y608 Human

SwissProt: Q91WK0 Mouse

SwissProt: Q4V7E8 Rat

Unigene: 475319 Human

Unigene: 302287 Mouse

Unigene: 20528 Rat

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