Rabbit Anti-BRD2 antibody | Sunlong Medical

Home > Product > Antibody > Rabbit Anti-BRD2 antibody

Bromodomain-containing protein 2; KIAA9001; RING3; O27.1.1; Really interesting new gene 3 protein; BRD2_HUMAN;

Cat:

SL12888R

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human BRD2:301-400/801

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: Lane 1: Molt-4 (Human) Cell Lysate at 30 ugLane 2: MDA-MB-231 (Human) Cell Lysate at 30 ugPrimary: Anti-BRD2 (SL12888R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 110-115 kDObserved band size: 130 kD

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]

Function:
May play a role in spermatogenesis or folliculogenesis.

Subunit:
Homodimer. Interacts with E2F1 and with histone H4acetylated at 'Lys-13'.

Subcellular Location:
Nucleus.

Similarity:
Contains 2 bromo domains.
Contains 1 ET domain.

SWISS:
P2588

Gene ID:
6046

Database links:

Entrez Gene: 6046 Human

Entrez Gene: 14312 Mouse

Entrez Gene: 294276 Rat

SwissProt: P2588 Human

SwissProt: Q7JJ13 Mouse

SwissProt: Q6MGA9 Rat

Picture

Sample:
Lane 1: Molt-4 (Human) Cell Lysate at 30 ug
Lane 2: MDA-MB-231 (Human) Cell Lysate at 30 ug
Primary: Anti-BRD2 (SL12888R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 110-115 kD
Observed band size: 130 kD

Product Feedback Wall