Rabbit Anti-C2orf3 antibody

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Chromosome 2 open reading frame 3; DNABF; GC rich sequence DNA binding factor; GCF; TCF 9; TCF9; Transcription factor 9; GCFC2_HUMAN.

Cat:

SL15014R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human C2orf3:601-700/781

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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GCF (GSLCrich sequence DNA-binding factor), also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNASF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GSLCrich sequences of β-Actin, EGFR and calcium-dependent protease (CANP) promoters. GCF contains multiple phosphoserine and phosphothreonine residues, and two GCF isoforms are produced due to alternative splicing events. GCF is considered a candidate for susceptibility to dyslexia (DYX3) as both genes reside in close proximity on human chromosome 2. Chromosome 2 is the second largest human chromosome and consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.

Function:
Factor that represses transcription. It binds to the GSLCrich sequences (5'-GCGGGGSLC3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed in tissues and cell lines.

Similarity:
Belongs to the GCF family.

SWISS:
P16383

Gene ID:
6936

Database links:

Entrez Gene: 6936 Human

Omim: 189901 Human

SwissProt: P16383 Human

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