Rabbit Anti-DNAJA2 antibody

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Cell cycle progression 3 protein; Cell cycle progression restoration gene 3 protein; CPR 3; CPR3; Dj3; DJA 2; DJA2; DnaJ (Hsp40) homolog subfamily A member 2; DNAJ; DnaJ homolog subfamily A member 2; DNAJA 2; Dnaja2; DNJ 3; Dnj3; DNJA2_HUMAN; HIRA interac

Cat:

SL13023R

Species Reactivity：

Mouse,(predicted: Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,Monkey,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNAJA2:151-250/412

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA2 (DnaJ homolog subfamily A member 2), also known as HIRA-interacting protein 4 or cell cycle progression restoration gene 3 protein, contains one CR-type zinc finger and is a co-chaperone of HSC 70.

Function:
Co-chaperone of Hsc70.

Subcellular Location:
Membrane.

Similarity:
Contains 1 CR-type zinc finger.
Contains 1 J domain.

SWISS:
O60884

Gene ID:
10294

Database links:

Entrez Gene: 10294 Human

Entrez Gene: 56445 Mouse

Entrez Gene: 16826 Rat

Omim: 611322 Human

SwissProt: O60884 Human

SwissProt: Q9QYJ0 Mouse

SwissProt: O35824 Rat

Unigene: 73678 Human

Unigene: 475573 Mouse

Unigene: 3904 Rat

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