FAKD3 is a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain. The members of this family are ubiquitously expressed and are generally most abundant in mitochondria-enriched tissues such as heart, skeletal muscle and brown-adipose tissue. Some members of this protein family may play a role in apoptosis. The protein encoded by this gene interacts with components of the mitochondrial respiratory and translation networks. A pseudogene of this gene is also present on chromosome 5. Alternative splicing results in multiple transcript variants.
Similarity:
Belongs to the FAST kinase family.
Contains 1 RAP domain.
SWISS:
Q14CZ7
Gene ID:
79072
Database links:
Entrez Gene: 79072 Human
SwissProt: Q14CZ7 Human
Unigene: 653162 Human
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