Fibronectins are multi-domain glycoproteins that bind to a variety of substances including collagen, actin, heparin, DNA, fibrin and fibronectin receptors. They are involved in a diverse array of important functions such as blood coagulation, wound healing, cell adhesion, cell differentiation and migration. FNDC4 (Fibronectin type III domain-containing protein 4), also known as FRCP1 (Fibronectin type III repeat-containing protein 1), is a 234 amino acid membrane protein that contains one fibronectin type-III domain, which serves as a binding site for DNA, heparin or the cell surface. The gene encoding FNDC4 is localized to human chromosome two, which houses over 1,400 genes and comprises nearly 8% of the human genome.
Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).
Similarity:
Contains 1 fibronectin type-III domain.
SWISS:
Q9H6D8
Gene ID:
64838
Database links:
Entrez Gene: 64838 Human
Entrez Gene: 64339 Mouse
GenBank: NP_073734.1 Human
Omim: 611905 Human
SwissProt: A6QPL2 Cow
SwissProt: Q9H6D8 Human
SwissProt: Q3TR08 Mouse
Unigene: 27836 Human
Unigene: 732184 Human
Unigene: 292544 Mouse
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