Rabbit Anti-G gamma7 antibody

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FLJ00058; GBG7_HUMAN; Gng7; GNGT7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-7 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7.

Cat:

SL13246R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human G gamma7:2-65/68

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum.

Function:
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity).

Subunit:
G proteins are composed of 3 units, alpha, beta and gamma.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer.

Similarity:
Belongs to the G protein gamma family.

SWISS:
O60262

Gene ID:
2788

Database links:

Entrez Gene: 618399 Cow

Entrez Gene: 2788 Human

Entrez Gene: 14708 Mouse

Entrez Gene: 58979 Rat

Omim: 604430 Human

SwissProt: P30671 Cow

SwissProt: O60262 Human

SwissProt: Q61016 Mouse

SwissProt: P43425 Rat

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