Home > Product > Antibody > Rabbit Anti-GGT7 heavy chain antibody
Gamma-glutamyltransferase 7 heavy chain; D20S101; dJ18C9.2; Gamma glutamyltransferase 4; Gamma glutamyltransferase 7; Gamma glutamyltransferase like 3; Gamma glutamyltransferase like 5; Gamma glutamyltranspeptidase 7; Gamma glutamyltranspeptidase like 3;
Cat:
SL13351R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 7 heavy chain:151-250/662<Extracellular>
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].

Function:
Cleaves glutathione conjugates.

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Isoform 3 interacts with FAM57A.

Subcellular Location:
Membrane; Single pass type II membrane protein.

Tissue Specificity:
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.

Similarity:
Belongs to the gamma-glutamyltransferase family.

SWISS:
Q9UJ14

Gene ID:
2686

Database links:

 



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