The GLIPR1 family consists of three core members, designated GLIPR1, GLIPR1L1 (GLIPR1-like protein 1) and GLIPR1L2, which form a distinct subgroup within the cysteine-rich secretory protein (CRISP), antigen 5 and pathogenesis-related 1 (CAP) superfamily. Each member of the CAP superfamily has a conserved N-terminal CAP domain and a distinct SLCterminal extension. CAP superfamily proteins are hypothesized to have roles in immunity, cell adhesion, carcinogenesis and male fertility. GLIPR1L1 is a 242 amino acid secreted protein. Highly expressed in testis, GLIPR1L1 exists as two isoforms produced by alternative splicing events. GLIPR1L1 is encoded by a gene that maps to human chromosome 12q21.1 and mouse chromosome 10 D2.
Subcellular Location:
Secreted.
Tissue Specificity:
Highly expressed in testis.
Similarity:
Belongs to the CRISP family.
SWISS:
Q6UWM5
Gene ID:
256710
Database links:
Entrez Gene: 256710 Human
Omim: 610395 Human
SwissProt: Q6UWM5 Human
Unigene: 567788 Human
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