C4orf34 (chromosome 4 open reading frame 34) is a 99 amino acid single-pass membrane protein that is encoded by a gene that maps to human chromosome 4. Human chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is located on chromosome 4. FGFR-3 is also encoded by a gene that maps to human chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Subcellular Location:
Membrane; Single-pass membrane protein (Potential).
SWISS:
Q96QK8
Gene ID:
201895
Database links:
Entrez Gene: 201895 Human
Entrez Gene: 68552 Mouse
Entrez Gene: 364154 Rat
SwissProt: Q96QK8 Human
SwissProt: Q91VT8 Mouse
SwissProt: Q498C7 Rat
Unigene: 57664 Human
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