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Rabbit Anti-GNPNAT1 antibody
Glucosamine 6-phosphate N-acetyltransferase (GNA1), also designated phosphoglucosamine transacetylase or phosphoglucosamine acetylase, belongs to the GNA1 subfamily of the larger acetyltransferase family of proteins. GNA1, a peripheral membrane protein containing one N-acetyltransferase domain, is expressed in the colon and maps to cytoband 14q22.1. The protein localizes to the Golgi apparatus and the endosome. It is important for UDP-GlcNAc biosynthesis pathway. GNA1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
Function:
Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2.
Subcellular Location:
Golgi apparatus membrane. Endosome membrane.
Similarity:
Belongs to the acetyltransferase family.
GNA1 subfamily.
Contains 1 N-acetyltransferase domain.
SWISS:
Q96EK6
Gene ID:
64841
Database links:
Entrez Gene: 64841 Human
Entrez Gene: 54342 Mouse
Entrez Gene: 498486 Rat
Entrez Gene: 512299 Cow
SwissProt: Q96EK6 Human
SwissProt: Q9JK38 Mouse
Unigene: 702056 Human
Unigene: 312945 Mouse
Unigene: 14702 Rat
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