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Rabbit Anti-GOLPH4 antibody
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008].
Function:
Plays a role in endosome to Golgi protein trafficking; mediates protein transport along the late endosome-bypass pathway from the early endosome to the Golgi.
Subcellular Location:
Golgi apparatus; Golgi stack membrane. Endosome membrane. Localizes to cis and medial Golgi cisternae. Probably cycles between early Golgi and distal compartments like endosome.
Post-translational modifications:
Phosphorylated probably by c-AMP-dependent kinases in its lumenal part.
O-glycosylated; modified by sialic acid residues.
N-glycosylated; N-glycans are probably of the complex type and modified by sialic acid residues.
Similarity:
Belongs to the GOLIM4 family.
SWISS:
O00461
Gene ID:
27333
Database links:
Entrez Gene: 27333 Human
Entrez Gene: 73124 Mouse
Entrez Gene: 310526 Rat
Omim: 601365 Human
SwissProt: O00461 Human
SwissProt: Q8BXA1 Mouse
SwissProt: Q5BJK8 Rat
Unigene: 14720 Human
Unigene: 249232 Mouse
Unigene: 24186 Rat
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